Cialis 20mg film-coated tablets containing the active ingredient tadalafil are used to treat erectile dysfunction (ED) in men. They are available in various strengths, including 20mg tablets.To treat ED, Cialis can be taken as needed, usually at least 30 minutes before sexual activity. The effect on sexual ability may last up to 36 hours. Alternatively, it can be taken regularly, once a day every day, in which case sexual activity can be attempted at any time between doses.